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Prenatal Testing (NIPT)

Non-invasive prenatal testing (NIPT) workflows are based on the analysis of circulating cell-free DNA (cfDNA) in maternal plasma. These workflows require highly efficient recovery of short DNA fragments, stable processing across large sample volumes and strong compatibility with downstream sequencing-based analysis.

This page provides an overview of relevant product categories and workflow considerations for NIPT and related prenatal testing applications. For selected workflows, deeper technical references and product guidance are also available through Magen.

Common Workflow Challenges

  • Efficient recovery of short cfDNA fragments from maternal plasma
  • Low fetal DNA fraction and sensitivity requirements for detection
  • Consistency across large sample volumes and batch processing workflows
  • Minimizing background genomic DNA contamination
  • Compatibility with downstream NGS library preparation and sequencing analysis

Relevant Product Categories

Circulating DNA Extraction Systems

NIPT workflows rely on efficient extraction of circulating DNA from plasma samples. Both column-based and magnetic bead-based systems are commonly used, depending on sample throughput, automation requirements and workflow preferences.

View related Angen products > Magen Purchase Guide > Magen workflow guidance >

Automation Platforms

High-throughput NIPT workflows often require automated extraction systems to improve consistency, reduce manual handling and support large sample processing volumes.

View related Angen products > Magen automation references >

Columns, Magnetic Beads and Workflow Components

Columns, magnetic beads and related workflow components are used in system development, optimization or customized workflows, especially for laboratories requiring flexible process design.

View related Angen products > Magen category references >

Further Technical References

For selected NIPT workflows, additional technical references, workflow-oriented guidance and broader product selection support are also available through Magen.

View related Magen Purchase Guide > Explore Magen Application page > See core Magen product pages >

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